RNA

Part:BBa_K4613453

Designed by: Yuchen Zhou   Group: iGEM23_NAU-CHINA   (2023-10-10)


motif 58.16

A specific RNA sequence, capable of binding with the protein PAL (BBa_K4613168), forms a stem-loop structure when inserted near the SD sequence of mRNA in a suitable manner. Upon binding with the photoactivatable PAL, this sequence inhibits the translation process. In other words, it establishes a translational-level optogenetic regulatory system in conjunction with PAL.


Reference

  1. Pietruschka G. Selection of an aptamer and development of a genetic device to control mRNA stability in response to light [D]. Bonn: Rheinische Friedrich-Wilhelms-Universität Bonn; 2022.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None