Part:BBa_K5332001:Hard Information

Brief introduction of katG KatG, a gene encoding hydroperoxidase in bacteria, is regulated by a variety of signaling molecules. At present, most studies focus on the influence of its mutation on bacterial resistance and its upstream pathway. Hydrogen peroxide is one of the reactive oxygen species (ROS). In aerobic breathing organisms, it is transferred from a single electron to oxygen to form a superoxide (O2 -), which is then catalyzed by superoxide dismutase. There are genes in Escherichia coli that can directly respond to excess H2O2, such as oxyR, which encodes that oxyR regulator can bind to katG promoter after oxidation to promote katG expression and transcription.