Coding

Part:BBa_K364308

Designed by: Bence Daniel   Group: iGEM10_Debrecen-Hungary   (2010-09-28)
Revision as of 15:13, 23 October 2010 by Daniel87 (Talk | contribs)

Human PXR LBD

Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by naturally occurring steroids, such as pregnenolone and progesterone.

PXR LBD with Rifampicin.jpg

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 134
    Illegal BglII site found at 245
    Illegal BamHI site found at 668
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
n/aHuman PXR LBD