Coding
Part:BBa_K5198003
Designed by: Robert Kaptur Group: iGEM24_Duke (2024-08-21)
antiCD19 scFv SJ25C1 WT
Single-chain variable fragment derived from the SJ25C1 antibody, which has strong affinity for the extracellular domain of CD19 [1]. By recognizing and binding to CD19, this scFv can potentially be used in therapeutic applications, where T-cells are engineered to express the scFv on their surface, enabling them to target and destroy CD19-positive B-cells.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
None |