Coding

Part:BBa_K5499007

Designed by: Hongjing Wang   Group: iGEM24_NWU-CHINA-A   (2024-09-29)
Revision as of 15:34, 29 September 2024 by Whj945 (Talk | contribs)


LAMP2A mature peptide

Lysosome-associated membrane protein 2, isoform A (LAMP2A), serves as a receptor and channel for transporting cytosolic proteins.

Usage and Biology

LAMP2A is a lysosome-associated membrane protein that is involved in the loading of soluble proteins containing specific amino acid sequences (such as the KFERQ motif) into nascent exosomes located at the endosomal limiting membrane. This process is known as exosomal LAMP2A cargo loading (e-LLoC) and is related to intercellular and interorgan communication.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Profile

Name: Lysosome-associated membrane protein 2, isoform A (LAMP2A)

Base Pairs:1146 bp

Origin: Homo sapiens, synthetic

Properties: a lysosome-associated membrane protein that serves as a receptor and channel for transporting cytosolic proteins

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Categories
Parameters
None