Part:BBa_K5332002:Design

Di-melittin (anti-inflammatory peptide)

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal NgoMIV site found at 42
  
• 1000
  COMPATIBLE WITH RFC[1000]

Design Notes

Despite modifications, the inherent cytotoxicity of melittin remains. When applying melittin, introducing amino acid mutations to alter its sequence could further reduce its toxicity to cells, enhancing its safety and applicability without affecting its bioactivity.

Source

The melittin peptide component was synthesized in the laboratory, with its sequence information sourced from the NCBI database.