Coding

Part:BBa_K5332002

Designed by: Qilin Yu   Group: iGEM24_NKU-China   (2024-09-26)
Revision as of 15:12, 26 September 2024 by Registry (Talk | contribs)

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Di-melittin (anti-inflammatory peptide)

We integrated the naturally occurring anti-inflammatory factor, melittin peptide, into the plasmid, which effectively reduces inflammation levels in the intestine. We refined and optimized it by connecting two melittin monomers with a linker to form a hairpin structure. This modification results in lower cytotoxicity and enhanced immune-stimulatory properties.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 42
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
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