Coding

Part:BBa_K5374018

Designed by: Langning Xu   Group: iGEM24_TestDaily-I-Beijing   (2024-09-19)
Revision as of 05:16, 19 September 2024 by Registry (Talk | contribs)

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CBD MMPs-VEGF (Collagen-Binding Domain from Matrix Metalloproteinases fused with Vascular Endothelia

The CBD from MMPs binds strongly to collagen, ensuring that the fusion protein localizes to collagen-rich environments. VEGF (Vascular Endothelial Growth Factor) is a key signaling protein that promotes blood vessel formation, critical for tissue repair and regeneration. By fusing VEGF with the collagen-binding domain, the protein can be directed specifically to collagen scaffolds, allowing for localized and sustained angiogenesis in tissue engineering applications.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 1426


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Categories
Parameters
None