Coding
Part:BBa_K5374018
Designed by: Langning Xu Group: iGEM24_TestDaily-I-Beijing (2024-09-19)
CBD MMPs-VEGF (Collagen-Binding Domain from Matrix Metalloproteinases fused with Vascular Endothelia
The CBD from MMPs binds strongly to collagen, ensuring that the fusion protein localizes to collagen-rich environments. VEGF (Vascular Endothelial Growth Factor) is a key signaling protein that promotes blood vessel formation, critical for tissue repair and regeneration. By fusing VEGF with the collagen-binding domain, the protein can be directed specifically to collagen scaffolds, allowing for localized and sustained angiogenesis in tissue engineering applications.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1426
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Categories
Parameters
None |