Coding
hok

Part:BBa_K5291010

Designed by: Rui Chen   Group: iGEM24_BNUZH-China   (2024-08-10)
Revision as of 10:48, 10 August 2024 by Registry (Talk | contribs)

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hok/mok

This gene comes from the hok/sok system in Escherichia coli. The hok is able to encode a kind of toxic protein that can result to the collapse of cell membrane potential, cellular respiratory arrest, cell shape changes, and ultimately cell death. The gene mok is overlapped with hok, and it encodes the lead peptide of the toxic protein. Both of them have a relatively longer half-life. The hok mRNA can be specifically binded with sok aitisense RNA, which inhibits the expression of the toxic protein.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None