Coding

Part:BBa_K4645017

Designed by: Meng Sun   Group: iGEM23_HZAU-China   (2023-10-11)
Revision as of 15:10, 12 October 2023 by Felicitysm (Talk | contribs)

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The gene encoding the histidine kinase receptor

When the extracellular concentration of CSP increases to a certain threshold, CSP binds to the extracellular domain of the histidine kinase receptor encoded by comD on the cell membrane, and the histidine kinase receptor is phosphorylated at aspartate to activate the intracellular response regulator protein ComE. The phosphorylated ComE protein binds to specific downstream gene promoters and regulates the expression of downstream target genes regulated by bacterial density sensing.


Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 544
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 544
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 544
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 544
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 544
  • 1000
    COMPATIBLE WITH RFC[1000]


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Parameters
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