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Part:BBa_K243028

Designed by: Freiburg Bioware09   Group: iGEM09_Freiburg_bioware   (2009-10-19)
Revision as of 22:28, 20 October 2009 by Sarah (Talk | contribs)

pMA FOS-Split Linker-Fok_a

Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. The heterodimeric Fos complex is one of the nine homologues of the AP-1 leucine zipper region. Via leucin zipper they interact among each other and with their bipartite domain they bind DNA. (Abate et al., Mol Cell Biol. 1991 July)

1fos bio r 250.jpg

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n/apMA FOS-Split Linker-Fok_a