Coding

Part:BBa_K4785005

Designed by: ZhengLin Li   Group: iGEM23_SUSTech-CHINA   (2023-10-10)
Revision as of 12:03, 10 October 2023 by Niganma8 (Talk | contribs)


high-mobility group box 1 (hmgb1)

A protein from the High Mobility Group-box superfamily is produced by this gene. The nuclear DNA-binding, non-histone protein that is encoded controls transcription and contributes to DNA organization. This protein participates in a number of biological activities, such as cell differentiation, inflammation, and tumor cell migration. This gene has several recognized pseudogenes. Multiple transcript variants that encode the same protein are produced through alternative splicing. Recent studies have found that the structure of HMGB1 is similar to DNABII protein in biofilm, which is responsible for stabilizing eDNA structure. Therefore, HMGB1 can be used to inhibit the growth of biofilm and disrupt mature biofilm. Therefore, our team registered this gene for the convenience of our team and subsequent teams.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 73


[edit]
Categories
Parameters
None