Composite
Part:BBa_K4619010
Designed by: KaMing Li Group: iGEM23_UCAS-China (2023-10-09)
PobR-Threshold Guard Switch
This composite part consists of four main components: the pobR, the pobR RBS, the pobR operator, the pobA/R dual-directional promoter, and the digitizer. The assembly process is as follows: The original pobA/R operon consists of six main components: pobA, pobA RBS, pobA/R dual-directional promoter, pobR operator, pobR RBS, and pobR. The pobA gene encodes an unnecessary enzyme that breaks down 4-HBA. Therefore, we remove the pobA and pobA RBS components but retain the entire promoter, pobR RBS, and pobR.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 462
Illegal AgeI site found at 154
Illegal AgeI site found at 675 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 595
Illegal SapI.rc site found at 1573
[edit]
Categories
Parameters
None |