Part:BBa_K4613010

Elastin-like Polypeptide(GVGVP)(15)

Elastin-like polypeptides(ELPs) are protein polymers derived from human tropoelastin. One of their key features is that they exhibit phase separation that is often reversible whereby samples remain soluble below a transition temperature(Tt) but form coacervates above Tt. They have many possible applications for sensing, activation, and nano assembly. Furthermore, they are non-immunogenic, substrates for proteolytic biodegradation, and can be decorated with functional peptides, proteins, and small molecules. The general structure of polymeric ELPs is (GVGVP)(15）, where the monomeric unit is Gly-Val-Gly-Val-Pro. The NAU-CHINA 2023 team used this part in versatile model systems for biomaterials development. The polymerization between ELPs containing SpyTags and one containing SpyCatchers can proceed efficiently in a wine production environment.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]