Regulatory
pArsR
Part:BBa_K190015
Designed by: Michael Verhoeven Group: iGEM09_Groningen (2009-07-15)
Revision as of 18:37, 18 October 2009 by PaulSchavemaker (Talk | contribs)
Arsenic Promoter (ArsR regulated)
This set includes promoters that are sensitive to various metals. The promoters are typically regulated by a receptor protein that binds to the metal ion or complex. |
Promoter sequence with recognition site for ArsR transcriptional regulator protein. ArsR binds to the promoter sequence in the absence of As and releases on binding of As, thereby activating transcription (1).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
1) C. Xu, W. Shi, and B.P. Rosen (1996) The Chromosomal arsR Gene of Escherichia coli Encodes a trans-acting Metalloregulatory Protein, The Journal of Biological Chemistry, Vol. 271, No. 5, Issue of February 2, pp. 2427–2432.
[edit]
Categories
Parameters
//function/regulation/transcriptional
//promoter
//regulation/negative
//promoter
//regulation/negative
negative_regulators | binding of As (III) to ArsR promotes dissociation of ArsR from the promoter region. |