Signalling

Part:BBa_K233307

Designed by: Swetha Srinivasan, Samit Watve, Mandar Phatak, Chinar Patil   Group: iGEM09_IBB_Pune   (2009-10-16)
Revision as of 08:53, 18 October 2009 by Swesrini (Talk | contribs)

TorA- This part is a export tag that utilizes the Twin Arginine Transport pathway(TAT)

The twin arginine translocation (Tat)4 pathway serves to transport folded proteins across energy-transducing membranes in archaea, bacteria, and the chloroplasts of plants (1–4). In bacteria, polypeptides exported via the Tat pathway include redox enzymes, virulence factors, periplasmic ligandbinding proteins, and enzymes involved in cell envelope biogenesis (5). Only proteins that can attain a folded state in the cytoplasm are competent for export via Tat (2, 6). Translocation across the membrane is initiated by the interaction of the signal peptide with the Tat machinery, which in Escherichia coli consists of the membrane proteins TatABC. The amino-terminal (n-) region contains the Tat consensus motif (S/T)RRXFLK, which includes the signature twin arginine dipeptide.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None