Coding

Part:BBa_K4586013

Designed by: Mohamed Mohamed Saad Aboelghare   Group: iGEM23_AFCM-Egypt   (2023-09-15)
Revision as of 12:03, 21 September 2023 by Mahmoud sayed (Talk | contribs) (→‎Part Description)


CX43

Part Description

This part is a transmembrane protein called connexin (CX43) that oligomerizes to form hexameric channels, called hemichannels, that can control the interaction and transfer of information between exosomes and cells of interest, which is called intercellular communication.

Usage

This part is implicated in our design to increase the amount of our therapeutic agent within the exosomes, as the CX43 transmembrane portion facilitates the loading of our cargo into the exosomes. Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 782


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Categories
Parameters
None