Coding

Part:BBa_K4586012

Designed by: Mohamed Mohamed Saad Aboelghare   Group: iGEM23_AFCM-Egypt   (2023-09-15)
Revision as of 09:00, 21 September 2023 by Mahmoud sayed (Talk | contribs) (→‎Part Description)


NadB

Part Description

NadB is the first enzyme in the NAD biosynthesis pathway that is useful in the production of ATP by increasing the metabolism rate of gene-modified cells through the FAD-dependent oxidation of L-aspartate to iminoaspartate, which has an essential role in exosome synthesis.

Usage

This part is implemented in our system to improve the efficacy of our therapeutic agent through increasing the default level of exosomes synthesis within our engineered MSCs.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 406
    Illegal AgeI site found at 1026
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None