Part:BBa_K4586006

Guide RNA

Part Description

Our guide RNA part is a specific RNA fragment that navigates the Cas system to the RNA or DNA target of interest according to its family and serves to make some changes, such as deletion, insertion, or alteration, to the target RNA or DNA by building complexes with them.

Usage

Our guide RNA is designed to navigate the Cas nuclease toward its specific target gene of interest, to knock-out the BAFF-R gene of auto-reactive B-Cell which is the gene responsible for the survival and maintenance of B-Cell that lead to apoptosis, and limit its pathogenic effect in RA.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]