RNA

Part:BBa_K4586006

Designed by: Mohamed Mohamed Saad Aboelghare   Group: iGEM23_AFCM-Egypt   (2023-09-15)
Revision as of 09:37, 20 September 2023 by Ahmed Mattar (Talk | contribs)


Guide RNA

Part Description

It is a fragment of RNA that serves as a roadmap for Cas enzymes that target RNA or DNA and builds complexes with them. These enzymes frequently remove, insert, or otherwise change the targeted RNA or DNA.

Usage

Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None