Protein_Domain

Part:BBa_K4607002

Designed by: Axel Rojero   Group: iGEM23_Tec-Chihuahua   (2023-07-21)
Revision as of 01:30, 22 July 2023 by Axelrohz24 (Talk | contribs)


Albumin binding domain (ABD)

abd-cds.jpg
Figure 1. Albumin binding domain diagram.

The albumin binding domain (ABD) from streptococcal protein G is capable of increasing the antibodies, proteins, and enzymes lifetimes [1].

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Usage and Biology

Results

Figure 2. 3D structure of the albumin binding domain, obtained with AlphaFold2.

References

[1] Seijsing, J., Sobieraj, A. M., Keller, N., Shen, Y., Zinkernagel, A. S., Loessner, M. J., & Schmelcher, M. (2018). Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion. Frontiers in Microbiology, 9. https://doi.org/10.3389/fmicb.2018.029


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Parameters
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