Coding

Part:BBa_K4497003

Designed by: Till Gundlach   Group: iGEM22_Munich   (2022-10-09)
Revision as of 12:11, 13 October 2022 by Rosareithmeir (Talk | contribs)

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Interleukin-11 receptor alpha chain signaling sequence


With signaling sequences, a protein can be directed to the appropriate cellular compartment within a cell.

When adding this signaling sequence to your synthetic protein, it is targeted to the cell membrane.


More information can be found here: http://www.signalpeptide.de/index.php?sess=&m=searchspdb&s=details&id=18521&listname=

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

Engelowski, E., Schneider, A., Franke, M., Xu, H., Clemen, R., Lang, A., Baran, P., Binsch, C., Knebel, B., Al-Hasani, H., Moll, J. M., Floß, D. M., Lang, P. A., & Scheller, J. (2018). Synthetic cytokine receptors transmit biological signals using artificial ligands. Nature Communications, 9(1). https://doi.org/10.1038/S41467-018-04454-8

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Parameters
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