Coding

Part:BBa_K4165188

Designed by: Esraa Elmligy   Group: iGEM22_CU_Egypt   (2022-10-01)
Revision as of 19:24, 11 October 2022 by Esraa Elmligy (Talk | contribs)

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Amyloid beta peptide 8

This part encodes two Amyloid 𝛽 peptides (BBa_K4165186) and (BBa_K4165187) conjugated together. It has the ability to bind to A𝛽 plaques inside the brain.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Dry Lab Characterization

Modeling

The peptide was modeled by several software (Alphafold-Apptest-Pepfold) and the best model from Alphafold scored 3 out of 6 according to our Quality assessment code. 

                       Figure 1. The 3D structure of peptide AB(39-42)-CLPFFD modeled by Alphafold


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Categories
Parameters
None