Coding

Part:BBa_K4241020

Designed by: Ng Tsz Chun   Group: iGEM22_HKU_HongKong   (2022-09-30)
Revision as of 15:45, 9 October 2022 by DaLegends6 (Talk | contribs)

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Cecropin B bacterial expression


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Overview

This part is Cecropin B, an antimicrobial peptide derived from the Cecropia moth. This specific sequence is optimized for bacterial expression.

Usage and Biology

Cecropins, a group of antimicrobial peptides fround primarily from insects, are a group of cationic antimicrobial peptides. Like most of the members of the group, Cecropin B has an amphipathic N-terminal segment and a largely hydrophobic C-terminal segment. These form a helix-hinge-helix structure, that is essential in maintaining antimicrobial effect.
This is simply the coding region of Cecropin B, to be used in typical bacterial protein expression systems and chassis.



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