Regulatory

Part:BBa_K4156078

Designed by: Zheng Huang   Group: iGEM22_LZU-CHINA   (2022-10-06)
Revision as of 08:26, 9 October 2022 by Hz (Talk | contribs)


-- No description --

pPepT is a hypoxia-sensing promoter, designed to sense oxygen.

Usage and Biology

It is mainly regulated by the transcriptional activator (FNR). In the absence of oxygen, the FNR binds to the [4Fe-4S]2+ cluster to generate a transcriptionally active homodimer. However, in the presence of oxygen, the [4Fe-4S]2+ cluster is degraded and the FNR dimer dissociates into inactive monomers.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None