Protein_Domain

Part:BBa_K4165018

Designed by: Esraa Elmligy   Group: iGEM22_CU_Egypt   (2022-09-30)
Revision as of 08:33, 8 October 2022 by Engy99 (Talk | contribs) (→‎Usage and Biology)


GGSGGGG Linker

A flexible 7 aa Glycine-Serine linker


Usage and Biology

A flexible linker with G and S aa residues with variable lengths. According to our project, 3 flexible linker required one for our clamps for binding of Tau or amyloid beta with our binding peptides. Second one for flexible linking between clamps and HTRA1 binding peptide . last one for binding our HTRA1 binding peptide with PDZ domain of our protease HTRA1. our linker with length [7 aa GGSGGGG ] was calculated by our team for testing how it would affect interaction of our mentioned parts with each other using Pymol Software.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None