Coding
RcsB

Part:BBa_K200000

Designed by: James Field   Group: iGEM09_Imperial College London   (2009-08-12)
Revision as of 08:21, 3 September 2009 by JamesField (Talk | contribs)

Colanic acid global regulator -> RcsB

RcsB is a receiver protein in a two component phosphorelay system, which acts as a positive regulator of a number of genes including capsule genes responsible for colanic acid production. 2 This is via the activation of the ugd/cps operon which is required for capsule synthesis.
Colanic acid is a heteropolymer containing glucose, galactose, fucose, and glucuronic acid.

It is important to note that RcsB is a global regulator found in many Enterobacteria. In Salmonella, up to 38 genes were found to be up-regulated by RcsB including ftsZ which affects the rate of cell division. 1

Usage and Biology

 Colanic acid is an exopolysaccharide secreted by some bacterial species to protect themselves from the environment that surrounds them.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

<biblio>

  1. 1 pmid=1597415
  2. 2 pmid=2404948

</biblio>


[edit]
Categories
//cds/biosynthesis
//chassis/prokaryote/ecoli
Parameters
None