Generator
Part:BBa_K4202007
Designed by: LIAOLIAO GAO Group: iGEM22_ZJU-China (2022-09-25)
PHY-Oxylimited-SpaBCTS
The subtilisin production module is mediated by a hypoxic promoter and functions through a gene cluster composed of SpaBCTS. The population of engineered Bacillus subtilis keeps growing in the cracks, consuming oxygen, and at the same time, the engineered bacteria penetrate deep into the tiny cracks, and the environment lacks oxygen, thus realizing hypoxic conditions, and the subtilisin production module is activated. However we failed to convince the function as the bacteria could only express the first protein under oxygen limitation environment.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 179
Illegal EcoRI site found at 1245
Illegal EcoRI site found at 3776
Illegal XbaI site found at 100
Illegal XbaI site found at 2024
Illegal SpeI site found at 95
Illegal PstI site found at 2674
Illegal PstI site found at 2992 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 179
Illegal EcoRI site found at 1245
Illegal EcoRI site found at 3776
Illegal SpeI site found at 95
Illegal PstI site found at 2674
Illegal PstI site found at 2992 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 179
Illegal EcoRI site found at 1245
Illegal EcoRI site found at 3776
Illegal BamHI site found at 2495
Illegal BamHI site found at 4765 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 179
Illegal EcoRI site found at 1245
Illegal EcoRI site found at 3776
Illegal XbaI site found at 100
Illegal XbaI site found at 2024
Illegal SpeI site found at 95
Illegal PstI site found at 2674
Illegal PstI site found at 2992 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 179
Illegal EcoRI site found at 1245
Illegal EcoRI site found at 3776
Illegal XbaI site found at 100
Illegal XbaI site found at 2024
Illegal SpeI site found at 95
Illegal PstI site found at 2674
Illegal PstI site found at 2992
Illegal AgeI site found at 2309
Illegal AgeI site found at 3317 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 361
Illegal SapI.rc site found at 2409
Illegal SapI.rc site found at 4919
Illegal SapI.rc site found at 6121
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Categories
Parameters
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