Part:BBa_K4268000

S-TIP37 Head-Tail Connector

Usage and Biology

S-TIP 37 is a T7-like cyanophage that virally infects its host via a lytic life cycle. T7-like phages are characterized by a complex symmetrical structure whose major structures are an icosahedral capsid (head) that houses the phage's virus, six tail-like fibers responsible for attachment to its host, and a "neck" region.

This part belongs to a collection that codes for a "ghost" phage shell that can be used to immobilize or deliver substances, to Synechococcus sp WH8109 or other emerging chassis in synthetic biology and cyanobacterial engineering.

File:T-suny-oneonta-t7-virus-structure.svg

Figure 1: A labeled visual detailing the various structures of a T7-like phage

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The Head-Tail Connector codes for the "neck" region of a T7-like phage. The "neck" serves two main purposes, binding the icosahedral capsid to the tail-like fibers and containing the molecular machinery that is responsible for injecting its contents into the target cyanobacteria.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal NheI site found at 346
  
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]