Protein_Domain

Part:BBa_K4175002:Design

Designed by: Li Xianxiu, Zhang Wanying   Group: iGEM22_ZJUintl-China   (2022-08-28)
Revision as of 06:21, 28 August 2022 by JasLee24 (Talk | contribs) (→‎References)

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human extracellular IL-6R


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 640
    Illegal PstI site found at 674
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 640
    Illegal PstI site found at 674
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 640
    Illegal PstI site found at 674
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 640
    Illegal PstI site found at 674
    Illegal NgoMIV site found at 192
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The sequence has been codon optimized.


Source

Human. The sequence is found through Ensembl https://asia.ensembl.org/Homo_sapiens/Transcript/Sequence_cDNA?db=core;g=ENSG00000160712;r=1:154405193-154469450;t=ENST00000368485

References

Kaur, S., Bansal, Y., Kumar, R., Bansal, G., 2020. A panoramic review of IL-6: Structure, pathophysiological roles and inhibitors. Bioorganic & Medicinal Chemistry 28, 115327. https://doi.org/10.1016/j.bmc.2020.115327