Coding

Part:BBa_K4421002

Designed by: YuJun Qu   Group: iGEM22_NMU_China   (2022-06-19)
Revision as of 02:34, 20 June 2022 by Registry (Talk | contribs)

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iCasp9

iCasp9 is a chemically-inducible kill switch.When exposed to a synthetic dimerizing drug such as AP1903, the inducible caspase 9 (iCasp9) becomes activated and leads to the rapid death of cells expressing this construct.iCasp9 can be activated by AP1903 that has proven safe at the required dose for optimum deletional effect

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 331
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 13
    Illegal BsaI.rc site found at 1153


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Categories
Parameters
None