Coding

Part:BBa_K3861007

Designed by: Mario Delgadillo   Group: iGEM21_Humboldt_Berlin   (2021-10-01)
Revision as of 22:31, 21 October 2021 by KristinHU (Talk | contribs)


fimH

FimH is the distal protein found at the tip of the type 1 fimbriae.1 The type 1 fimbriae plays a role in the adherence of Salmonella Typhimurium to the host cells, whereby mannose-containing glycoproteins can be bound by FimH.
As a part of our project "Target Taxi", we aim to fuse rBC2LCN (BBa_K3861001), a lectin able to bind specifically to several cancer cell types, to FimH for surface display.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

1. Kisiela, D. I. et al. Allosteric catch bond properties of the fimh adhesin from Salmonella enterica serovar typhimurium. J. Biol. Chem. (2011) doi:10.1074/jbc.M111.237511.

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Categories
Parameters
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