Coding

Part:BBa_K3962350

Designed by: Siheng Li   Group: iGEM21_Leiden   (2021-10-13)
Revision as of 18:37, 21 October 2021 by SihengLi (Talk | contribs)


HOK - Toxin in Hok/Sok

HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOK is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded. The gel electrophoresis is shown as below: 800px-T--Leiden--Parts-HOK.png

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None