Coding
Part:BBa_K3794000
Designed by: Harshraj Bumia Group: iGEM21_KCL_UK (2021-09-30)
Revision as of 18:08, 21 October 2021 by Harshbumia (Talk | contribs)
PVFP-5
Perna viridis foot protein-5 (PVFP-5), is one of the first adhesive proteins secreted by the mussel foot from the Perna viridis mussel species.
PVFP-5 is an adhesive protein that can be utilised in biomedical and therapeutic applications due to its low immunogenicity and non-cytotoxicity in the body. It can be used as a bioadhesive coating for medical implants, such as a 3D printed scaffold / nerve channel for axonal regeneration.
There is an encoded N-terminal 6xHis tag and TEV cleavage site for protein purification via a Ni-NTA column. Upstream of the 6xHis tag, there is a start codon to allow for transcriptional initiation.
This part has been synthesised by IDT as a composite, which can be found at
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