Part:BBa_K4003006

pET-24a-PPM1A

Usage and Biology

Studies have shown that an Alzheimer’s patient is born every three seconds. As of 2019, more than 52 million people worldwide are living with Alzheimer’s disease. The patients in China achieved a quarter of the total. In the same year, an expert in Alzheimer’s research in the United States said,” They're maybe more people who go undiagnosed. Nowadays millions of people worldwide are suffered from the pain of Neurodegenerative diseases (NIH) and currently, no one in the world can completely cure these kinds of diseases, all we can do is slow down the process.

So our product is targeting those patients who suffer from the disease related to the microglia Inflammation, such as Alzheimer’s.

1. Purification principle of recombinant human PPM1A protein:

Fig1. ÄKTA™ pure protein purifier..

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal NheI site found at 5075
  
• 21
  INCOMPATIBLE WITH RFC[21]

  Illegal BglII site found at 4964
  Illegal BglII site found at 6045
  Illegal BamHI site found at 5108
  Illegal XhoI site found at 5148
  Illegal XhoI site found at 6516
  
• 23
  COMPATIBLE WITH RFC[23]
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal NgoMIV site found at 137
  Illegal NgoMIV site found at 3184
  Illegal NgoMIV site found at 3344
  Illegal NgoMIV site found at 4932
  
• 1000
  COMPATIBLE WITH RFC[1000]