Coding

Part:BBa_K3952004

Designed by: B. Liam, D. Amanda, R. Jazmine, S. Brianna   Group: iGEM21_SUNY_Oneonta   (2021-10-01)
Revision as of 17:50, 18 October 2021 by Jazmine124 (Talk | contribs)


LRP4 (Syndactylous Hooves)

Located within chromosome 11 of the Bos taurus genome, the LRP4 gene codes for an LDL receptor-related protein, a protein involved in the formation of the cattle's hooves. Studies have reported an inheritable syndactylous allele within the LRP4 gene that leads to congenital syndactyl (also known as mule foot) in cattle. This part contains the syndactylous allele of the LRPR gene where a substitution of nucleotides at positions 4863 and 4864, becomes AT. Part: BBa_K3952003 is the wild-type version of the LRP4 gene and its nucleotides are CG at positions 4863 and 4864. The substitution occurring in the syndactylous allele results in two adjacent single-nucleotide polymorphisms.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 325
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None