Composite

Part:BBa_K3981015

Designed by: Yulin Peng   Group: iGEM21_AHUT_China   (2021-10-14)
Revision as of 13:37, 14 October 2021 by Registry (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)


pET28a-his-linker-her2-linker-ISZ-sTRAIL

Compared with his-linker-ISZ-sTRAIL, this plasmid has one more artificial antibody expressing Her2, which further enhances the targeting effect of the secreted protein on cancer cells. The role of the artificial Her2 antibody is to recognize specific receptors on the surface of breast cancer cells. At the same time, the Her2 antibody can enhance the targeting effect of the treatment and reduce the damage of the fusion protein to other human cells. At the same time, we have also done relevant cell experiments to verify that the Her2 protein is more damaging to cancer cells than the none.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None