Generator
Part:BBa_K3962343:Design
Designed by: Siheng Li Group: iGEM21_Leiden (2021-10-11)
arabinose-mediated inducible expression of toxin RelE
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 1205
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1144
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 979
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI site found at 961
Design Notes
pBAD has been intensively investigated and has tight regulation upon downstream genes. It is the most suitable promoter for regulating toxin genes and preventing their toxic effects. For RelE, it has also been used as a part of a kill switch.
Source
All parts come from the iGEM registry.