Protein_Domain

Part:BBa_K4040007

Designed by: Tong Yin   Group: iGEM21_NMU_China   (2021-09-02)
Revision as of 00:34, 15 September 2021 by Ytong (Talk | contribs)


CD8 Transmembrane Domain

The transmembrane domain of the CAR performs a signal transduction role after the interaction between the S protein of pseudo- SARS-CoV-2 and the CARs. In this part, we used the CD8 hinge and the CD8 transmembrane domain presented in the αCD19 CAR for T cell to construct the transmembrane domain of our CAR-macrophage.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 22
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None