Coding

Part:BBa_K3351008

Designed by: Yu Zhang   Group: iGEM20_NWU-CHINA-A   (2020-09-08)
Revision as of 14:03, 19 October 2020 by ZZ-NWU (Talk | contribs)

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PhaP, amphiphilic polyhydroxyalkanoates (PHAs)-granule-associated protein.

Summary

PhaP is the dominant protein naturally attached on the surface of the PHA granules. This protein contains a hydrophobic granule binding domain and a cytosol-facing hydrophilic domain. PhaP-tagged proteins could interact with various types of hydrophobic surfaces. So PhaP is an effective anchor to hydrophobic polymer surface for surface functionalization. PhaP allows a more flexible display of AMP on the biomaterial surface and demonstrates its efficacy for wound healing.



Reference

[1] Xue Q, Liu XB, Lao YH, Wu LP, Wang D, Zuo ZQ, Chen JY, Hou J, Bei YY, Wu XF, Leong KW, Xiang H, Han J. Anti-infective biomaterials with surface-decorated tachyplesin I. Biomaterials. 2018 Sep;178:351-362. doi: 10.1016/j.biomaterials.2018.05.008. Epub 2018 May 9. PMID: 29778319.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None