Translational_Unit

Part:BBa_K3522001

Designed by: Kong Yangyang   Group: iGEM20_NOFLS_YZ   (2020-10-16)
Revision as of 06:07, 17 October 2020 by Kimmy2020 (Talk | contribs)


T7 pro-His-FXR-LBD-T7 ter

BBa_K3522001 contains T7 promoter, His tag, FXR ligand-binding domain(FXR-LBD), and T7 terminator. Farnesoid X receptor (FXR) belongs to a member of the nuclear receptor Superfamily and has been reported to be associated with glucose metabolism. For example, in FXR−/− mice, the level of hepatic gluconeogenic gene expression was decreased after fasting, while blood glucose level and the hepatic glucose production in response to pyruvate challenge were declined.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal XhoI site found at 749
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None