Part:BBa_K3561007
W8W9A6C11
This peptide is expected to be a palladium reducing peptide. This peptide is modified by our team from the palladium binding peptide A6C11 (Coppage et al., 2013). We have incorporated a tryptophan residue into the peptide as it was reported that tryptophan is capable of reducing palladium (Chiu et al., 2010). We chose a double tryptophan structure at residues 8 and 9 as it was said that a double tryptophan is more effective than a single tryptophan structure in gold(Tan et al., 2010). We would like to investigate whether a double tryptophan will be more effective in palladium. We also want to investigate what effects will there have if we inserted the tryptophan residue at different positions. This peptide has an isoelectric point of 9.0, a molecular weight of 1.40 kDa and hydrophobicity of 32.98. The alanine residue at positions 4 and 6 has a minimal binding with palladium while the cysteine residue at position 11 has a strong binding with palladium, it was suggested that this may have higher efficiency(Coppage et al., 2013). The serine and threonine residues at position 2 and 10 are also reported to be important in binding with palladium(Sarikaya et al., 2003). The amino acid sequence of the peptide is TSNAVAPWWRCL.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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