Reporter

Part:BBa_K3380151:Design

Designed by: Alexandru Popov   Group: iGEM20_Edinburgh   (2020-10-08)
Revision as of 13:45, 8 October 2020 by Alexandru popov (Talk | contribs) (→‎Design Notes)


DIR2s-Apt fluorescent RNA aptamer


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Source

The DIR2s-Apt is an artificial RNA aptamer obtained by testing its binding properties to the DIR (dimethylindole red) fluorogen.

References

Tan, X., Constantin, T.P., Sloane, K.L., Waggoner, A.S., Bruchez, M.P. and Armitage, B.A., 2017. Fluoromodules consisting of a promiscuous RNA aptamer and red or blue fluorogenic cyanine dyes: selection, characterization, and bioimaging. Journal of the American Chemical Society, 139(26), pp.9001-9009.