Part:BBa_K3098006

PgD5

The part contains the coding sequence for the antimicrobial peptide PgD5, which shows the ability to inhibit the growth of some filamentous fungi. Some research about the peptide suggests that this kind of effect comes into being by disrupting the membrane structure of the cell. The expression of PgD5 in E.coli has been done in the research in order to get its purified solution, and a strong inhibition has been tested in experiment. For the reason above, we chose this special peptide in our project as a defender of the silk relics.

The tertiary structure of PgD5 has been shown here. For more information about the antimicrobial peptide, you can take the paper we have read as a reference.Identification of defensin-encoding genes of Picea glauca: characterization of PgD5, a conserved spruce defensin with strong antifungal activity

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal AgeI site found at 91
  
• 1000
  COMPATIBLE WITH RFC[1000]