RNA

Part:BBa_K2989005

Designed by: Meng Chen   Group: iGEM19_Nanjing_NFLS   (2019-10-14)
Revision as of 15:54, 19 October 2019 by Tinanana (Talk | contribs)


Ce-HBsAg-70

Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg. It, together with miR-HBsAg-70, helps to form a regulation system.

Usage

Ce-HBsAg-70 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-70 is expressed. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg It, together with miR-HBsAg-70, helps to form a regulation system.

T--Nanjing_NFLS--Parts_BBa_K2989005.jpg

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None