Composite

Part:BBa_K3030002

Designed by: Yirui Xu   Group: iGEM19_XJTLU-CHINA   (2019-10-13)
Revision as of 16:53, 13 October 2019 by Registry (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)


Excitatory Amino Acid Transporter 2 with C/D Box from Homo Sapiens

This part contains EAAT2 protein that may transport glutamate, which is an universal excitatory neurotransmitter, from cleft and extracellular matrix, and alleviate the excitotoxicity induced by the overhigh glutamate. The part also contains C/D box which may binds to L7Ae transfected and expressed on inner side of exosome membrane, and help hold the mRNA of EAAT2 on exosomes.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None