Coding
Part:BBa_K2963000:Design
Designed by: Haixin Gao Group: iGEM19_JNU-China (2019-09-05)
PgsC - a submit of poly-gamma-glutamic acid synthetase
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 251
Illegal EcoRI site found at 310 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 251
Illegal EcoRI site found at 310 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 251
Illegal EcoRI site found at 310 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 251
Illegal EcoRI site found at 310 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 251
Illegal EcoRI site found at 310
Illegal NgoMIV site found at 85 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
When we express the CapC protein heterologously in corynebacterium glutamicum, we add Ptac promoter and a short RBS, which can be recognized by corynebacterium glutamicum. And simultaneously, we add T7 terminater used for stopping translation in time.
Source
capC sequence can be found in the Bacillus licheniformis