![](https://parts.igem.org/images/partbypart/icon_coding.png)
Coding
PlyF307-SQ
Part:BBa_K3182003
Designed by: Oliver Hild Walett Group: iGEM19_Linkoping_Sweden (2019-07-11)
PlyF307-SQ8C
Acinetobacter phage endolysin, designed to target Acinetobacter baumannii. This part was designed to be assembled with BBa_K3182010.
![](/wiki/images/3/35/T--Linkoping_Sweden--MechofAction.png)
Figure 1. General mechanism of action when the antimicrobial agent is fused to BBa_K3182010 which contains the linker, thrombin site and cellulose binding domain. The cellulose binding domain enables the attachment of antimicrobial agents (such as antimicrobial peptide or enzyme) to the cellulose. This also inactivates the agents when they are expressed in its bacterial host. Later, when the bandage comes in contact with thrombin in the blood, the antimicrobial agents will be activated upon cleavage of its thrombin site.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |