Coding

Part:BBa_K2765021

Designed by: Jun Li   Group: iGEM18_BIT-China   (2018-09-15)
Revision as of 20:27, 17 October 2018 by NarrrEn (Talk | contribs)


yno1

Yno1(also known as aim14，short for Altered Inheritance rate of Mitochondria or ygl160w) encodes a genuine NADPH oxidase (NOX enzymes), which is located in the endoplasmic reticulum (ER) and produces superoxide in a NADPH-dependent fashion. Experiments have shown that overexpress yno1 can increase the accumulation of intracellular ROS.

T--BIT-China--PartRegulator_yno1_Fig1_Position.png

reference: https://www.yeastgenome.org/locus/S000003128

T--BIT-China--PartRegulator_yno1_Fig2_Overexpress.png

Fig.2 overexpress yno1


T--BIT-China--PartRegulator_yno1_Fig3_process_of_Electron_transformation.png

Fig. 3 process of Electron transformation

Overexpression yno1 gene can causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p



Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 1569


[edit]
Categories
Parameters
None