Reporter
Part:BBa_K2611003:Design
Designed by: Qinling Qiu Group: iGEM18_SCU-China (2018-10-17)
Spacer J23101-RFP
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 30
Illegal NheI site found at 53 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 640
Illegal AgeI site found at 752 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
The spacer sequence and the NGG site should be closely to the promoter (no space in this part).
Source
The spacer sequence is generated by a special algorithm.[1] And the backbone we used is from BBa_K516132. [1]Didovyk A, Borek B, Hasty J, et al. Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9[J]. Acs Synthetic Biology, 2016, 5(1):81-88.